Copper Peptides for Skin: What GHK-Cu Is and How to Use It

Copper peptides have gone from a niche ingredient to one of the most requested names in skincare. Here's what they are, why people love them, and how to get the most out of a copper peptide serum.

What copper peptides are

The best-known copper peptide is GHK-Cu: a small chain of three amino acids (glycine, histidine and lysine) bound to a copper ion. GHK occurs naturally in the body, including in skin, and it has a strong natural attraction to copper. Skincare formulas use it because it's small enough to work well in a lightweight serum.

Why people use them

• Firmer-looking skin: copper peptides are popular in routines aimed at skin that looks firmer and smoother.
• Hydration: serums with copper peptides are typically water-based and pair well with humectants that help skin feel plump and hydrated.
• Face and neck: the neck is often overlooked, and a light serum makes it easy to treat both in one step.
• Gentle daily use: most people can use a copper peptide serum once or twice a day without the sting associated with some stronger actives.

How to use a copper peptide serum

1. Cleanse and pat skin dry.
2. Apply 2 to 3 drops of Copper Peptides Serum to the face and neck, pressing it in gently.
3. Follow with your moisturizer. For an extra-hydrating finish, layer our Methylene Blue Complex Cream on top.
4. In the morning, finish with sunscreen.

What to pair it with (and what to space out)

Copper peptides pair nicely with hyaluronic acid, ceramides and niacinamide. Many people prefer to use strong exfoliating acids and high-strength vitamin C at a different time of day than their copper peptide serum, for example vitamin C in the morning and copper peptides at night. Retinoids can be alternated on different evenings while your skin gets used to both.

How long until you see a difference?

Skin renews itself over several weeks, so consistency is everything. Use your serum daily for 4 to 8 weeks and compare photos taken in the same light.

Patch test first

As with any new skincare, apply a small amount to your inner arm or jawline for a day or two before using it all over. Stop using it if you notice irritation.

Build a full routine

Our Copper Peptide collection includes the serum plus shampoo, conditioner and body wash made with copper peptides, so you can carry the same care from face to scalp to body. Browse everything in Skincare.

This article is for general information only and isn't medical advice. These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure or prevent any disease.